Assembly Biosciences, Inc. is a clinical-stage biotechnology company advancing a new class of oral therapeutics for the treatment of hepatitis B virus (HBV) infection and novel oral biotherapeutics for disorders associated with the microbiome.
Assembly's team has significant experience in infectious disease drug discovery and development and has collectively helped bring more than ten anti-infective products to the market. The company's HBV-Cure Program is aimed at increasing cure rates and is advancing multiple drug candidates that address upstream and downstream viral targets in the HBV lifecycle for possible use in combination therapy. The company's Microbiome Program consists of a fully integrated platform that includes a robust strain identification and selection process, methods for strain isolation and growth under cGMP conditions, a large and growing strain library and inventory, and a patent pending delivery system, Gemicel®, which allows for targeted oral delivery of live biologic and conventional therapies to the lower GI tract. The lead program from this platform, AB-M101, is in development for the treatment of C. difficile infection, and several other indications are in development.
Assembly has recruited a diverse team of outstanding scientists whose shared commitment to advancing science and enhancing the health and well-being of patients creates a vibrant culture and drives our efforts to develop curative treatments for the millions of people worldwide infected by HBV and CDI.
Discover, develop, and commercialize novel drugs with the potential to cure challenging infectious diseases, focusing initially on a functional cure for chronic HBV and on a new class of medicines that uses our patent pending microbiome technologies to treat disease in entirely new ways.
Assembly is building a fully integrated infectious disease-focused company based on its proprietary technologies:
Assembly has facilities in Indiana, San Francisco and New York. Our team consists of approximately 100 management and technical employees and consultants with deep expertise in drug discovery, development and commercialization. This team is augmented by a highly experienced Board of Directors and world-class scientific and clinical advisers.